144 - Makowski, M., Lisowski, M., Maciag, A., Wiktor, M., Szlachcic, A., Lis, T. (2010) Two pentadehydropeptides with different configurations of the DeltaPhe residues. Acta Crystallogr C 66, o119-123. [PubMed]

143 - Pomorski, A., Otlewski, J., Krężel, A. (2010) The high Zn(II) affinity of tetracysteine tag affects its fluorescent labeling with biarsenicals. ChemBioChem 11, 1214-1218. [PubMed]

142 - Sreedhara, A., Flengsrud, R., Prakash, V., Krowarsch, D., Langsrud, T., Kaul, P., Devold, T.G. & Vegarud, G.E. (2010) A comparison of effects of pH on the thermal stability and conformation of caprine and bovine lactoferrin. Int. Dairy J. 20, 487-494. [link]

141 - Grela, P., Krokowski, D., Gordiyenko, Y., Krowarsch, D., Robinson, C.V., Otlewski, J., Grankowski, N., Tchórzewski, M. (2010) Biophysical Properties of  the Eucaryotic Ribosomal Stalk. Biochemistry 49, 924-933. [PubMed]

140 - Crack, J.C., den Hengst, C.D., Jakimowicz, P., Subramanian, S., Johnson, M.K., Buttner, M.J., Thomson, A.J., Le Brun, N.E. (2009) Characterization of [4Fe-4S]-containing and cluster-free forms of Streptomyces WhiD. Biochemistry. 48(51), 12252-12264. [PubMed]

139 - Mateja, A., Szlachcic, A., Downing, M. E., Dobosz, M., Mariappan, M., Hedge, R. S., Keenan, R. J. (2009) The Structural Basis of Tail-anchored Membrane Protein Recognition by Get3. Nature 461(7262), 361-366. [PubMed]

138 - Crack, J.C., den Hengst, C.D., Jakimowicz, P., Subramanian, S., Johnson, M. K., Buttner, M. J., Thomson, A. J., Le Brun, N. E. (2009) Characterization of [4Fe-4S]-Containing and Cluster-Free Forms of Streptomyces WhiD. Biochemistry 48, 12252-12264. [PubMed]

137 - Kubiak, A., Jakimowicz, P., Polanowski, A. (2009) A Kazal-type serine proteinase inhibitor from chicken liver (clTI-1) Purification, primary structure, and inhibitory properties. International Journal of Biological Macromolecules 45, 194-199. [PubMed]

136 - Zakrzewska, M., Zhen, Y., Wiedlocha, A., Olsnes, S., Wesche, J. (2009) Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane. Biochemistry 48, 7209-7218. [PubMed]

135 - Zakrzewska, M., Wiedlocha, A., Szlachcic, A., Krowarsch, D., Otlewski, J., Olsnes, S. (2009) Increased Protein Stability of FGF1 Can Compensate for Its Reduced Affinity for Heparin. J. Biol. Chem.284, 25388-25403. [PubMed]

134 - Kubiak, A., Jakimowicz, P., Polanowski, A. (2009) A Kazal-type serine proteinase inhibitor from chicken liver (clTI-1): purification, primary structure, and inhibitory properties. Int J Biol Macromol. 45(2), 194-199. [PubMed]

133 - Jaskolski, M., Fernandes, H., Bujacz, A., Jelen, F., Jasinski, M., Kachlicki, P., Otlewski, J. & Sikorski, M. (2009) Cytokinin-induced Structural Adaptability of a Lupinus luteus PR-10 Protein. FEBS J.276, 1596-1609. [PubMed]

132 - Szlachcic, A., Zakrzewska, M., Krowarsch, D., Os, V., Helland, R., Smalås, A. & Otlewski, J. (2009) Structure of a Highly Stable Mutant of Human Fibroblast Growth Factor-1. Acta Cryst. D65, 67-73.[PubMed]

131 - Jelen, F., Lachowicz, P., Apostoluk, W., Mateja, A., Derewenda, Z.S. & Otlewski, J. (2009) The Molecular Basis of GTPase Selectivity of the GAP Domain of GrafGAP. J. Struct. Biol. 165, 10-18.[PubMed]

130 - Zakrzewska, M., Marcinkowska, E., Wiedlocha, A. (2008) FGF-1: from biology through engineering to potential medical applications. CRC Crit. Rev. Clin. Lab. Sci. 45, 91-135. [PubMed]

129 - Goscinski, M.A., Suo, Z.H., Nesland, J.M., Chen, W.T., Zakrzewska, M., Wang, J., Zhang, S., Florenes, V.A., Giercksky, K.E. (2008) Seprase, dipeptidyl peptidase IV and urokinase-type plasminogen activator expression in dysplasia and invasive squamous cell carcinoma of the esophagus. A study of 229 cases from Anyang Tumor Hospital, Henan Province, China. Oncology. 75, 49-59. [PubMed]

128 - Sorensen, V., Zhen, Y., Zakrzewska, M., Haugsten, E.M., Walchli, S., Nilsen, T., Olsnes, S., Wiedlocha, A. (2008) Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus. Mol. Cell. Biol. 28, 4129-4141. [PubMed]

127 - Otlewski, J. (2008) The World of Proteins. In: Ku Interdyscyplinarności... Różne Oblicza Rzeczywistości (E. Dobierzewska-Mozrzymas, J. Gajda-Krynicka and A. Jezierski, eds.) Wydawnictwo Uniwersytetu Wrocławskiego, Wrocław, pp. 135-142. [link]

126 - Smietana, K., Kasztura, M., Paduch, M., Derewenda, U., Derewenda, Z.S. & Otlewski, J. (2008) The Degenerate Specificity of the PDZ Domains in the RhoA-specific Nucleotide Exchange Factors PDZRhoGEF and LARG. Acta Biochim. Polon. 55, 269-280. [PubMed]

125 - Kiedzierska, A., Czepczynska, H., Smietana, K. & Otlewski, J. (2008) Expression, Purification, and Crystallization of Cysteine-rich Protein Muskelin in Escherichia coli. Protein Exp. Purif. 60, 82-88.[PubMed]

124 - Sharina, I.G., Jelen, F., Bogatenkova, E.P., Thomas, A., Martin, E., and Murad, F. (2008) Alpha1 soluble guanylyl cyclase (sGC) splice forms as potential regulators of human sGC activity. J. Biol. Chem.30, 15104-15113. [PubMed]

123 - Kiedzierska, A., Smietana, K., Czepczynska, H. & Otlewski, J. (2007) Structural Similarities and Functional Diversity of Eucaryotic Discoidin-like Domains. Biochim. Biophys. Acta 1774, 1069-1078.[PubMed]

122 - Zawilak-Pawlik, A., Kois, A., Stingl, K., Boneca, I.G., Skrobuk, P., Jakimowicz, P., Lurz, R., Zakrzewska-Czerwińska, J., Labigne, A. (2007) HobA - a novel protein involved in initiation of chromosomal replication in Helicobacter pylori. Mol Microbiol. 65(4), 979-94. [link]

121 - Paduch, M., Biernat M., , Stefanowicz P., Derewenda, Z.S., Szewczuk Z. & Otlewski J. (2007) Application of Bivalent Peptides to Study PDZ Domain-mediated Interactions. ChemBioChem 8, 443-452.[PubMed]

120 - Zakrzewska, M., Krowarsch, D., Wiedlocha, A., Olsnes, S. Otlewski, J. (2006) Structural Requirements of FGF-1 for Receptor Binding and Translocation into Cells. Biochemistry 45, 15338-15348.[PubMed]

119 - Jakimowicz, P., Tello, M., Meyers, C.L., Walsh, C.T., Buttner, M.J., Field, R.A., Lawson, D.M. (2006) The 1.6-A resolution crystal structure of NovW: a 4-keto-6-deoxy sugar epimerase from the novobiocin biosynthetic gene cluster of Streptomyces spheroides. Proteins. 63(1), 261-265. [PubMed]

118 - Zdanowski, K., Doughty, P., Jakimowicz, P., O'Hara, L., Buttner, M.J., Paget, M.S., Kleanthous, C. (2006) Assignment of the zinc ligands in RsrA, a redox-sensing ZAS protein from Streptomyces coelicolor. Biochemistry. 45(27), 8294-8300. [PubMed]

117 - Drulis-Fajdasz, D., Jelen, F., Oleksy, A. & Otlewski, J. (2006) Novel Pepetide Recognized by RhoA GTPase. Acta Biochim. Polon. 53, 515-524. [PubMed]

116 - Oleksy, A., Opalinski, L., Derewenda, U., Derewenda, Z.S. & Otlewski, J. (2006) The Molecular Basis of RhoA Specificity in the Guanine Nucleotide Exchange Factor PDZ-RhoGEF" J. Biol. Chem. 281, 32891-32897. [PubMed]

115 - Tello, M., Jakimowicz, P., Errey, J.C., Freel Meyers, C.L., Walsh, C.T., Buttner, M.J., Lawson, D.M., Field, R.A. (2006) Characterization of Streptomyces spheroides NovW and revision of its functional assignment to a dTDP-6-deoxy-D-xylo-4-hexulose 3-epimerase. Chem. Commun. (Camb). 10, 1079-1081. [link]

114 - Pasternak, O., Bujacz, G.D., Fujimoto, Y., Jelen, F., Otlewski, J., Sikorski, M.M. & Jaskolski, M. (2006) Unusual Zeatin Binding Revealed by Atomic-resolution Structure of Cytokinin-specific Binding Protein. Plant Cell 18, 2622-2634. [PubMed]

113 - Bialas, A., Grembecka, J., Krowarsch, D., Otlewski, J., Potempa, J. & Mucha, A. (2006) Exploring the Sn Pockets in Gingipains by Newly Developed Inhibitors: Structure-based Design, Chemistry and Activity. J. Med. Chem. 49, 1744-1753. [PubMed]

112 - Mateja, M., Cierpicki, T., Paduch, M.,Derewenda, Z.S. & and Otlewski, J. (2006) The Dimerization Mechanism of Lis1 and Its Implication for Proteins Containing the LisH Motif. J. Mol. Biol. 357, 621-631.[PubMed]

111 - Chmiel, A.A., Radlinska, M., Pawlak, S.D., Krowarsch D., Bubnicki, J.M., & Skowronek, K.J. (2005) A theoretical model of restriction endonuclease NlaIV in complex with DNA, predicted by fold recognition and validated by site-directed mutagenesis and circular dichroism spectroscopy. Protein Eng. Des. Sel.18, 181-189. [PubMed]

110 - Zakrzewska, M., Krowarsch, D., Wiedlocha, A., Olsnes, S. Otlewski, J. (2005) Highly Stable Mutants of Human Fibroblast Growth Factor-1 Exhibit Prolonged Biological Action. J. Mol. Biol. 352, 860-875.[PubMed]

109 - Jakimowicz, P., Cheesman, M.R., Bishai, W.R., Chater, K.F., Thomson, A.J., Buttner, M.J. (2005) Evidence that the Streptomyces developmental protein WhiD, a member of the WhiB family, binds a [4Fe-4S] cluster. J Biol Chem.280(9), 8309-8315. [PubMed]

108 - Krowarsch, D., Zakrzewska, M., Smalås, A.O. & Otlewski, J. (2005) Structure-Function Relationships in Serine Protease - Bovine Pancreatic Trypsin Inhibitor Interaction. Protein Peptide Lett. 12, 403-407.[PubMed]

107 - Otlewski, J., Jelen, F., Zakrzewska, M. & Oleksy, A. (2005) The Many faces of Protease - Protein Inhibitor Interaction. EMBO J. 24, 1303-1310. [PubMed]

106 - Orlowski, M., Szyszka, M., Kowalska, A., Grad, I., Zoglowek, A., Rymarczyk, G., Dobryszycki, P., Krowarsch, D., Rastinejad, F., Kochman, M. & Ozyhar, A. (2004) Plasticity of the Ecdysone Receptor DNA-Binding Domain. Mol. Endocrinol. 18, 2166-2184. [PubMed]

105 - Dobryszycki, P., Kolodziejczyk, R., Krowarsch, D., Gapinski, J., Ożyhar, A. & Kochman M. (2004) Unfolding and Refolding of Juvenile Hormone Binding Protein, Biophys. J. 86, 1138-1148. [PubMed]

104 - Otlewski, J. (2004) Professor Michael Laskowski, Junior. (Professor Michael Laskowski - obituary) Postępy Biochemii 50(4). [link]

103 - Czapinska, H., Helland, R., Smalås, A.O. & Otlewski, J. (2004) Crystal Structures of Five Bovine Chymotrypsin Complexes with P1 BPTI Variants. J. Mol. Biol. 344, 1005-1020. [PubMed]

102 - Zakrzewska, M., Krowarsch, D., Wiedlocha, A. & Otlewski, J. (2004) Design of Fully Active FGF-1 Variants with Increased Stability. Design of Fully Active FGF-1 Variants with Increased Stability. Protein Eng. Des. Sel. 17, 603-611.[PubMed]

101 - Derewenda, U., Oleksy, A., Stevenson, A.S., Korczynska, J., Dauter, Z., Somlyo, A.P., Otlewski, J., Somlyo, A.V., & Derewenda, Z.S. (2004) The Crystal Structure of RhoA in Complex with the DH/PH Fragment of PDZRhoGEF, an Activator of the Ca(2+) Sensitization Pathway in Smooth Muscle. Structure12, 1955-1965. [PubMed]

100 - Borek, D., Michalska, K., Brzezinski, K., Kisiel, A., Podkowinski, J., Bonthron, D. T., Krowarsch, D., Otlewski, J. & Jaskolski, M. (2004) Expression, Purification, and Catalytic Activity of Lupinus luteus Asparagine β-amidohydrolase and Its Escherichia coli Homolog. Eur. J. Biochem. 271, 3215-3226. [PubMed]

99 - Kim, M.H., Cooper, D., Oleksy, A., Devedjiev, Y., Derewenda, U., Reiner, O., Otlewski, J. & Derewenda, Z.S. (2004) The Structure of the N-terminal Domain of the Product of the Lissencephaly Gene Lis1 and Its Functional Implications. Structure 12, 987-998. [PubMed]

98 - Oleksy, A., Barton, H., Devedjiev, Y., Derewenda, U., Otlewski, J. & Derewenda, Z.S. (2004) Preliminary Crystallographic Analysis of the Complex of the Human GTPase RhoA with the DH-PH Tandem of PDZRhoGEF. Acta Cryst. D60, 740-742. [PubMed]

97 - Schrøder-Leiros, H.K., Brandsdal, B.O., Andersen, O.A., Os, V., Leiros, I., Helland, R., Otlewski, J., Willassen, N.P. & Smalås, A.O. (2004) Trypsin Specificity as Elucidated by LIE Calculations, X-ray Structures and Association Constant Measurements. Protein Science 13, 1056-1070. [PubMed]

96 - Czepas, J., Devedjiev, J., Krowarsch, D., Derewenda, U., Otlewski, J. & Derewenda, Z.S. (2004) The Impact of Lys to Arg Surface Mutations on the Crystallization of the Globular Domain of RhoGDI. Acta Cryst. D60, 275-280.[PubMed]

95 - Zawilak, A., Durrant, M.C., Jakimowicz, P., Backert, S., Zakrzewska-Czerwińska, J. (2003) DNA binding specificity of the replication initiator protein, DnaA from Helicobacter pylori. J Mol Biol. 334(5), 933-947. [PubMed]

94 - Jakimowicz, P., Freel Meyers, C.L., Walsh, C.T., Buttner, M.J., Lawson, D.M. (2003)  Crystallization and preliminary X-ray studies on the putative dTDP sugar epimerase NovW from the novobiocin biosynthetic cluster of Streptomyces spheroides. Acta Crystallogr D Biol Crystallogr. 59(Pt 8), 1507-1509. [PubMed]

93 - Jelen, F., Oleksy, O., Śmietana, K. & Otlewski, J. (2003) PDZ Domains - Common Players in the Cell Signaling. Acta Biochim. Polon. 50, 985-1017. [PubMed]

92 - Krowarsch, D., Cierpicki, T., Jelen, F. & Otlewski, J. (2003) Canonical Protein Inhibitors of Serine Proteases. Cell. Mol. Life Sci. 60, 2427-2444. [PubMed]

91 - Helland, R., Czapinska, H., Leiros, I., Olufsen, M., Otlewski, J. & Smalås, A.O. (2003) Structural Consequences of Accommodation of Four Non-cognate Amino-acid Residues in the S1 Pocket of Bovine Trypsin and Chymotrypsin. J. Mol. Biol. 333, 845-861. [PubMed]

90 - Koscielska-Kasprzak, K. & Otlewski, J. (2003) Amyloid Forming Peptides Selected from Phage-Displayed ββα Libraries. Protein Science 12, 1675-1685. [PubMed]

89 - Koscielska-Kasprzak, K., Cierpicki, T. & Otlewski, J. (2003) Importance of α-helix N-capping Motif in Stabilization of ββα Fold. Protein Science 12, 1283-1289. [PubMed]

88 - Kim, M.H, Cierpicki, T., Derewenda, U., Krowarsch, D., Feng, Y., Devedjiev, Y., Dauter, Y., Walsh, C.A., Otlewski, J., Bushweller, J.H. & Derewenda, Z.S. (2003) The DCX-Domain Tandems of Doublecortin and Doublecortin-like Kinase: Implications for Microtubule Regulation. Nature Struct. Biol. 10, 324-333. [PubMed]

87 - Kang, B.S., Cooper, D., Jelen, F., Devedjiev, Y., Derewenda, U., Dauter, Z., Otlewski, J. & Derewenda, Z.S. (2003) PDZ-tandem of Human Syntenin: Crystal Structure and Functional Properties. Structure 11, 459-468. [PubMed]

86 - Cierpicki, T., Kim, M.H., Otlewski, J., Derewenda, Z.S. & Bushweller, J.H. (2003) Letter to the Editor: Assignment of 1H, 13C and 15N Resonances of the N-terminal Domain of Human Doublecortin. J. Biomol. NMR 25, 81-82.[PubMed]

85 - Li, W., Stevenson, C.E., Burton, N., Jakimowicz, P., Paget, M.S., Buttner, M.J., Lawson, D.M., Kleanthous, C. (2002) Identification and structure of the anti-sigma factor-binding domain of the disulphide-stress regulated sigma factor sigma(R) from Streptomyces coelicolor. J Mol Biol. 323(2), 225-236. [PubMed]

84 - Pruchnik, F.P., Jakimowicz, P., Ciniuk, Z., Zakrzewska-Czerwinska, J., Opolski, A., Wietrzyk, J., Wojdat, E. (2002) Rhodium (III) complexes with polypyridyls and pyrazole and their antitumor activity. Inorg. Chim. Acta. 334, 59-66 [link]

83 - Mateja, A., Devedjiev, Y., Krowarsch, D., Longenecker, K., Dauter, Z., Otlewski, J. & Derewenda Z.S. (2002) The Impact of Glu->Ala, and Glu->Asp Mutations on the Crystallization Properties of RhoGDI. Crystal Structure of RhoGDI at 1.3 Å Resolution. Acta Cryst. D58, 1983-1991. [PubMed]

82 - Cierpicki, T. & Otlewski, J. (2002) NMR Structures of the Two Variants of Bovine Pancreatic Trypsin Inhibitor (BPTI) Reveal Unexpected Influence of Mutations on Protein Structure and Stability. J. Mol. Biol. 321, 647-658. [PubMed]

81 - Cierpicki, T., Zhukow, I., Byrd, A.R. & Otlewski, J. (2002) Hydrogen Bonds in Human Ubiquitin Reflected in Temperature Coefficients of Amide Protons. J. Magnetic Resonance 157, 178-181. [PubMed]

80 - Martin, T.W., Dauter, Z., Devedjiev, Y., Jelen, F., Sheffield, P.J., Otlewski, J., Derewenda, Z.S. & Derewenda, U. (2002) Molecular Basis of Mitomycin C Resistance in Streptomyces: Crystal Structures of the MRD Protein with and without a Drug Derivative. Structure 10, 933-942. [PubMed]

79 - Buczek, O., Krowarsch, D. & Otlewski, J. (2002) Thermodynamics of Single Peptide Bond Cleavage in Bovine Pancreatic Trypsin Inhibitor (BPTI). Protein Science 11, 924-932. [PubMed]

78 - Buczek, O., Koscielska-Kasprzak, K., Krowarsch, Dadlez, M. & Otlewski, J. (2002) Analysis of Serine Proteinase - Inhibitor Interaction by Alanine Shaving. Protein Science 11, 806-819. [PubMed]

77 - Paduch, M., Jelen, F. & Otlewski, J. (2001) Structure of Small G Proteins and Their Regulators. Acta Biochim. Polon. 48, 829-850. [PubMed]

76 - Kiczak, L., Kasztura, M., Koscielska-Kasprzak, K., Dadlez, M. & Otlewski, J. (2001) Selection of Potent Chymotrypsin and Elastase Inhibitors from M13 Phage Library of Basic Pancreatic Trypsin Inhibitor (BPTI). Biochim. Biophys. Acta 1550, 153-163. [PubMed]

75 - Cierpicki, T. & Otlewski, J. (2001) Amide Proton Temperature Coefficients as Hydrogen Bond Indicators in Proteins. J. Biomol. NMR 21, 249-261. [PubMed]

74 - Otlewski, J., Jaskólski, M., Buczek, O., Cierpicki, T., Czapińska, H., Krowarsch, D., Smalås, A.O., Stachowiak, D., Szpineta, A. & Dadlez, M. (2001) Structure-Function Relationship of Serine Protease - Protein Inhibitor Interaction. Acta Biochim. Polon. 48, 419-428. [PubMed]

73 - Addlagatta, A., Krzywda, S., Czapinska, H., Otlewski, J. & Jaskolski, M. (2001) Ultra High Resolution Structure of BPTI. Acta Cryst. D57, 649-663. [PubMed]

72 - Krowarsch, D. & Otlewski, J. (2001) Amino-Acid Substitutions at the Fully Exposed P1 Site of Bovine Pancreatic Trypsin Inhibitor Affect Its Stability. Protein Science 10, 715-724. [PubMed]

71 - Lu, S. M., Lu, W., Qasim, M. A., Anderson, S., Apostol, I., Ardelt, W., Bigler, T., Chiang, Y. W., Cook, J., James, M. N. G., Kato, I., Kelly, C., Kohr, W., Komiyama, T., Lin, T.-Y., Ogawa, M., Otlewski, J., Park, S.-J., Qasim, S., Ranjbar, M., Tashiro, M., Warne, N., Whatley, H., Wieczorek, A., Wieczorek, M., Wilusz, T., Wynn, R., Zhang, W. & Laskowski, M.Jr. (2001) Predicting the Reactivity of Proteins from their Sequence Alone. Kazal Family of Protein Inhibitors of Serine Proteinases. Proc. Natl. Acad. Sci. USA 98, 1410-1415. [PubMed]

70 - Młynarz, P., Valensina, D., Kozłowski, H., Kowalik-Jankowska, T., Otlewski, J., Gagelli, G. & Gagelli, N. (2001) Coordination Ability Towards CuII of the 29-Amino Acid Residue Trypsin Inhibitor of Squash and Two of Its Analogues. J. Chem. Soc. Dalton Trans. 645-652. [link]

69 - Wesołowska, O., Krokoszynska, I., Krowarsch, D. & Otlewski, J. (2001) Enhancement of Chymotrypsin-Inhibitor/Substrate Interactions by 3M NaCl. Biochim. Biophys. Acta 1545, 78-85. [PubMed]

68 - Pruchnik, F.P., Jakimowicz, P., Ciniuk, Z., Stanislawek, K., Oro, L.A., Tejel, C., Ciriano M.A. (2001) Rhodium wires on binuclear acetate-bridged complexes. Inorg. Chem. Comm. 4(1), 19-22. [link]

67 - Pruchnik, F.P., Jakimowicz, P., Ciniuk, Z. (2001) Synthesis and structural characterisation of new one-dimensional rhodium complexes. Inorg. Chem. Comm. 4(12), 726-729. [link]

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